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Lilly will pay $125 million upfront and up to $835 million in potential milestones for Rigel's lead RIPK1 inhibitor, R552.
February 18, 2021
By: Kristin Brooks
Managing Editor, Contract Pharma
Eli Lilly and Co. and Rigel Pharmaceuticals, Inc. entered an exclusive global license agreement and strategic collaboration to co-develop and commercialize Rigel’s R552, a receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitor, for all indications including autoimmune and inflammatory diseases. Lilly will also lead all clinical development of brain penetrating RIPK1 inhibitors in central nervous system (CNS) diseases. Rigel’s lead RIPK1 inhibitor, R552, has will...
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